MATHESON, along with its affiliates and partners, provides a suite of innovative solutions for the biomedical industry. We deliver dependable expertise and help navigate you through strict regulations to provide you with a solution that fits your goals.
Stable Isotopes such as water-18O (98 and 10 atom %) and oxygen-18O are used for medical diagnostics and imaging applications such as Positron Emission Tomography (PET).
MATHESON’S sister company, Taiyo Nippon Sanso, provides the world’s largest capacity for water-18O with GMP capability at three (3) plants.
Water-17O is used as a tracer in MRI imaging for the measurement of permeability and blood flow in the brain as well as kinetic analysis of cerebrospinal fluid. Please read this article to learn more about the advantages of using Water-17O MRI imaging:
We have also published two research papers describing the use of Water-17O MRI imaging:
- Indirect MRI of 17O-Labeled Water Using Steady-State Sequences: Signal Simulation and Preclinical Experiment – An evaluation of the feasibility of steady-state sequences for indirect 17O brain imaging.
- Indirect Proton MR Imaging and Kinetic Analysis of 17O-Labeled Water Tracer in the Brain – An evaluation of the feasibility of steady-state sequences for 17O imaging on kinetic analysis of the brain parenchyma and cerebrospinal fluid.